In vitro screening of antioxidant activity and total polyphenol content of selected medicinal plants collected in Ca Mau province

Abstract

Natural antioxidants play a crucial role in the prevention and management
of various diseases. This study aimed to evaluate the antioxidant activity and total
polyphenol content of six selected extracts from 23 crude extracts obtained from
different parts of 12 medicinal plants belonging to the families Boraginaceae,
Acanthaceae, Asteraceae, Apocynaceae, Oxalidaceae, Clusiaceae, Arecaceae,
Vitaceae, Bignoniaceae, Cucurbitaceae, and Zingiberaceae [1]. The plant materials
were exhaustively extracted with 96% ethanol, and the solvents were removed under
reduced pressure to yield crude extracts.
All extracts exhibited antioxidant activity, among which the stem extract of Cayratia
trifolia and the mesocarp extract of Borassus flabellifer demonstrated the strongest
antioxidant effects, with IC₅₀ values of 107.68 mg/mL and 86.26 mg/mL, respectively.
The Borassus flabellifer mesocarp extract also showed the highest total polyphenol
content, reaching 185.17 ± 0.97 mg GAE/g extract. This is the first report on the antioxidant potential and total polyphenol content of medicinal plants collected in Ca
Mau Province. The findings suggest that these medicinal plants possess promising
potential for the prevention and management of metabolism-related disorders in Ca
Mau in particular and in Vietnam in general.